To determine whether CaR deficiency influences the effects of dietary calcium and exogenous PTH on bone growth and BMD, 3-week-old pups were fed by Pth+/–CaR+/– dams that received either the normal or the high-calcium diet, or pups were administrated exogenous PTH. This evidence concerns the gene PTH and hyperinsulinemic hypoglycemia, familial, 4.