These include the genes codingfor alsin (ALS2), vesicle associated membrane protein B (VAPB) [2], senataxin (SETX) [3], TAR-DNA-bindingprotein (TDP-43) [4], fused in sarcoma or translocated in liposarcoma(FUS/TLS) [5],[6], and optineurin (OPTN) [7]. This evidence concerns the gene OPTN and sarcoma.