BMI1 and ovarian cancer: With respect to the regulation of specific oncogenes or cancer-promoting genes by miRNAs in ovarian cancer, it was reported that miR-15a and miR-16 control oncogenic Bmi-1 expression as well as targeting anti-apoptotic Bcl-2 in ovarian cancer cell lines [89], while miR-9, was found to inhibit ovarian cancer growth by regulating NF-kB1 expression [90].