In addition, an increase in the expression of miR-200 family members correlated with the decreased expression of ZEB transcription factors, which are known to promote epithelial-mesenchymal transition (EMT) by repressing the expression of critical adhesion molecules of epithelial cells and miR-200 family targets ZEB1/2, suggesting that miR-200 family plays a role in ovarian tumor progression [56]. The gene discussed is ZEB1; the disease is ovarian neoplasm.