In cancer cells, activation of Met by HGF induces nuclear translocation of β-catenin, leading to activation of TCF/LEF-mediated gene transcription (Danilkovitch-Miagkova et al. 2001; Monga et al. 2002; Rasola et al. 2007; reviewed by Nelson and Nusse 2004). The gene discussed is HGF; the disease is cancer.