The fact that we have previously found relevant NRAMP1 polymorphisms in Crohn's patients [6], T1DM patients [4] and MS patients [5], together with the positive results given by IS900 PCR, suggests that there is a strong possibility of MAP being involved with autoimmune responses in MS just in the same manner as it did in Crohn's and T1DM. Here, SLC11A1 is linked to type 1 diabetes mellitus.