Future studies will focus on putative regulation of adipogenic stem cells by NET4 and its possible involvement in Laminopathies such as Dunnigan-type familial partial lipodystrophy (FPLD; [42], [43]) or mandibuloacral dysplasia (MADA; [44]). Here, TMEM53 is linked to mandibuloacral dysplasia with type A lipodystrophy.