SMTNL1 and chronic intestinal pseudoobstruction: In addition, reduction of SRF (Srf in mice) and smoothelin-A (Smtnl1) found in CIPO [43],[44],[49] is also seen in the mutant SM and/or SMCs (for Srf, see Figure 5C, E and Figure S1; for Smtnl1, see the NCBI GEO array dataset GSE21738 deposited in this study).