This revealed that eleven of the zebrafish genes (11/149; 7.4%) have human homologs that are causally implicated in various cancers (Table 6): CBFB, CBL, EXT1, GATA2, MSI2, NCOA2, NCOA4, PBX1, PRDX5, SMARCB1, and TSHR (Table 6). The gene discussed is MSI2; the disease is cancer.