The same SH2B3 SNP rs3184504 identified in our study has previously been associated with multiple other traits, including blood pressure [27], [28], blood eosinophil number [29], myocardial infarction [29], celiac disease [30], type I diabetes [31], LDL-cholesterol [32], asthma [29], blood platelet number [33], hemoglobin concentration [34] and hematocrit [34]. Here, SH2B3 is linked to type 1 diabetes mellitus.