Major up-regulated probes following co-exposure of AQ and SP included genes having a cysteine and histidine-rich domain (CHORD) containing zinc-binding protein 1, mainly involved in calcium ion binding, the solute carrier family 28 (sodium-coupled nucleoside transporter) member 3 gene involved in ion transport, the Kelch-like 2 Mayven (Drosophila) gene involved in actin binding, the integrin beta 8 gene involved in cell adhesion, the gene for suppression of tumorigenicity (colon carcinoma) involved in cell migration and mortality factor 4 like 1 gene involved in cell proliferation. This evidence concerns the gene KLHL2 and colon carcinoma.