FOXM1 and pulmonary edema: The role of forkhead box M1 (FoxM1) in the molecular mechanisms of endothelial barrier repair following a vascular injury was recently studied by Zhao et al.47 In response to LPS, the endothelial cell restricted FoxM1 deficient mouse (FoxM1 CKO) displayed a significantly prolonged increase of the lung vascular permeability and the mortality due to severe pulmonary edema.