In serial sections, areas of tumour positive for cytoplasmic Hsp70 tended to exhibit strong cytoplasmic Bag-1 staining (Figure 5) and there was a clear association between intensity of Hsp70 and Bag-1 staining, with a correlation between cytoplasmic Bag-1 and Hsp70 staining intensity scores (P<0.001; correlation coefficient=0.462). This evidence concerns the gene BAG1 and neoplasm.