We likewise observed upregulation of several SLE-associated IFN response genes, including OASL (2.2-fold), PLSCR1 (2.3-fold), EIF2AK2 (2.4-fold), and IFI27, the last of which exhibited the highest degree of increased gene expression (7.2-fold) in our study. The gene discussed is IFI27; the disease is systemic lupus erythematosus.