In the Pan-VEGF Blockade for the Treatment of Retinopathy of Prematurity (BLOCK-ROP) study (ClinicalTrials.gov Identifier: NCT01232777), intravitreal injection of 0.625 or 0.75 bevacizumab (Avastin®), an anti-VEGF antibody, will be compared with standard of care laser for type 1 prethreshold ROP diagnosed at 30–36 postmenstrual weeks. Here, VEGFA is linked to retinopathy of prematurity.