On day 31 post-implantation, the mean tumor volume was 678.70 ± 121.73 mm3 in FA-PEAs:pVHL-treated mice, whereas tumor had 935.23 ± 112.14, 950.40 ± 41.98 mm3 in FA-PEAs:pVITRO2-treated and PBS group respectively (Figure 4, p < 0.05), which indicated VHL gene therapy achieved about 30% inhibiting rate of tumor growth. The gene discussed is VHL; the disease is neoplasm.