According to previous studies, sulfated oligosaccharides were thought to suppress tumor angiogenesis, growth, and metastasis primarily by their competitive inhibition of the cleavage of heparan sulfate-growth factor complex, thus reducing the release of growth factors, such as vascular endothelial growth factor and basic fibroblast growth factor from the microenvironmental matrix [21]. The gene discussed is VEGFA; the disease is neoplasm.