We speculate that H1N1-mediated elevations of FPG might be the result of multiple factors' combinations caused by H1N1 virus infection, such as inflammatory stress, multiple organ impairment, and so on, while the changes of plasma glucose were not caused by H1N1 actions on insulin secretion by pancreatic β-cells or decreasing sensitivity to insulin. The gene discussed is INS; the disease is viral infectious disease.