To do so, we used the BCP-ALL cell lines Reh and EU-3 and the lymphoblastoid cell line TK6, all of which express wt p53, and examined the inhibitory effect of cAMP signaling on DNA damage-induced cell death in the presence of the NF-κB inhibitor Bay 11-7082. Here, NFKB1 is linked to acute lymphoblastic leukemia.