Among the few upregulated mRNAs (Table 5), IL11 was the most increased (>4-fold), followed by inhibin-βA, IL6, and TGFβ2. However, IL-11 was not detectable in both DMD and healthy sera, whereas measurements of inhibin-βA and TGF-β2 revealed no difference between DMD and healthy sera (inhibin-βA: control 256.0 ± 61.0 pg/mL; DMD 237.0 ± 74.0 pg/mL; TGF-β2: control 123.0 ± 91.0 pg/mL; DMD 117.0 ± 54.0 pg/mL; differences not significant), thus pointing out that their effect could be exerted only locally in the bone microenvironment in response to systemic factors. This evidence concerns the gene TGFB2 and Duchenne muscular dystrophy.