IL6 and Duchenne muscular dystrophy: Skeletal muscle has been identified recently as an endocrine organ producing a number of “myokines“ belonging to different cytokine families, and IL-6 was discovered as a myokine because it systemically increases during physical exercise.(39,40) Interestingly, IL-6 also has been observed to be increased in dystrophic muscles(41) and therefore may represent one of the mediators of the bone phenotype in DMD.