To exclude the possibility that the divergent PRLR expression profiles of PCI-6A and PCI-6B cells might be because of culture selection, we evaluated PRLR expression in sections of the primary tumour and the metachronously developed lymph node metastasis by immunohistochemistry (Figure 2). The gene discussed is PRLR; the disease is metastatic malignant neoplasm in the lymph nodes.