Moreover, MCP1 -2581G and -362C were shown to enhance promoter activity in vitro in individuals from Korea (MCP1 -2581G) and in Caucasians (MCP1 -2581G and -362C), respectively [8,9,15], consistent with studies indicating that in pulmonary TB MCP-1 plasma levels are elevated [3,4]. This evidence concerns the gene CCL2 and pulmonary tuberculosis.