核糖核苷酸还原酶M1(ribonucleotide reductase M1, RRM1)的表达水平与肿瘤细胞对吉西他滨耐药密切相关。本研究旨在探讨晚期非小细胞肺癌(non-small cell lung cancer, NSCLC)中RRM1蛋白的表达水平与吉西他滨联合顺铂(GP方案)化疗疗效的关系。. The gene discussed is RRM1; the disease is non-small cell lung carcinoma.