In these human bladder tumors, over-expression of PDGFR-α was correlated with nodal metastasis and overexpression of c-Met or c-Met/Axl/PDGFR-α showed the most significant correlation with poor patient survival (p < 0.01) followed by c-Met/PDGFR-α, PDGFR-α, c-Met/Axl, and Axl/PDGFR-α (p < 0.05) (table 2). The gene discussed is PDGFRA; the disease is urinary bladder neoplasm.