By using micro-angiography and immunohistochemistry approaches, we showed that regular consumption of RWPs in the drinking water decreased C26 tumour vascularization in BALB/C mice as a consequence of decreased expression of major proangiogenic factors including VEGF, matrix metalloproteinase 2 and 9, and cyclooxygenase-2 [97]. This evidence concerns the gene VEGFA and neoplasm.