We have previously reported on the presence of FOXP3+ T cells in native atherosclerosis, and observed that the numbers of Treg in native atherosclerosis, when expressed as a percentage of the total number of CD3+ T cells, were significantly lower when compared to normal skin and inflammatory dermatoses (psoriasis, spongiotic dermatitis, lichen planus and Leishmaniasis) [18], [19]. The gene discussed is FOXP3; the disease is leishmaniasis.