Revision of the histology of the initial biopsy as well as analysis of the second biopsy revealed the presence of ALK-positive DLBCL with expression of CD138, VS38c, CD38 and EMA, fine granular cytoplasmic ALK-staining and expression of the immunoglobulin kappa light chain as well as gamma heavy chain (Figure 1). The gene discussed is MUC1; the disease is diffuse large B-cell lymphoma.