As demonstrated in Figure 1B, microglia upregulate PCNA expression as early as day 3 post-infection compared to microglia from sham-infected mice (13.75±3.35% vs. 7.13±2.47%) with the most significant increase observed at day 7 post-infection (35.07±2.56% vs. 14.05±4.85%). This evidence concerns the gene PCNA and infection.