Both CD4+ and CD8+ T cells express similar levels of B7-H1 at day 7 post-infection (Figure 5A) (90.3%+ vs. 98.9%+), while CD8+ T cells express elevated levels of PD-1 represented by percent positive (48.8%+ vs. 57.2%+) and mean fluorescence intensity (Figure 5B) (B7-H1: 335.40±39.451 [CD4+ T cells] vs. 886.8±32.772 [CD8+ T cells]; (PD-1: 553.6±8.992 [CD4+ T cells] vs. 363.30±55.310 [CD8+ T cells]). The gene discussed is CD8A; the disease is infection.