Out of these 30 genes, six NB-associated genes were selected; i) the pre-disposition genes ALK and PHOX2B, ii) MYCN and CCND1which are amplified in 20-35% and 3-6% of sporadic neuroblastomas respectively [13,30,40], and iii) NTRK1 and BIRC5 which have been found to be differentially expressed between subsets of NB [41,42]. The gene discussed is BIRC5; the disease is neuroblastoma.