Moreimportantly, the availability of genome-wide data across these three majorpopulation groups allowed us to evaluate the transferability and relevance of thepreviously established genomic regions that are involved in the pathogenesis of T2D.In addition, we investigated the genetic architecture at CDKAL1 andHHEX/IDE/KIF11, showingevidence of population-specific effects, allelic heterogeneity and LD variations atthese loci across our three populations. The gene discussed is KIF11; the disease is type 2 diabetes mellitus.