It is noteworthy that the variants for which we were able to detect anassociation in our study were mostly discovered in the earlier wave of genome-widescans for T2D (including CDKAL1, HHEX/IDE/KIF11,IGFBP2, SLC30A8 and FTO)[5]–[7], [51]. Here, CDKAL1 is linked to type 2 diabetes mellitus.