The availability of three GWAS scans across three genetically heterogeneouspopulations offers a unique opportunity to explore the genetic architectureunderlying the two loci CDKAL1 andHHEX/IDE/KIF11 thatshowed the strongest evidence of association with T2D in more than 1 populationand in our meta-analysis. The gene discussed is KIF11; the disease is type 2 diabetes mellitus.