These genome-wide association studies(GWAS) have identified a number of novel loci harboring common variants that areassociated with an increased risk of T2D [4]–[11], adding to the loci previouslyidentified by candidate gene studies (PPARG[12],KCNJ11[13]–[14],WFS1[15]–[16]) and linkagestudies TCF7L2[17]–[19]). Here, WFS1 is linked to type 2 diabetes mellitus.