On mRNA level, BDNF inhibited mRNA expression of brain TNF-α after stroke at both 6 h (0.39 ± 0.01 versus 1.00 ± 0.06, n = 6, P < .05, Figure 5(b)) and 24 h (0.77 ± 0.04 versus 0.91 ± 0.06, n = 6, P < .05, Figure 5(b)) of reperfusion. The gene discussed is TNF; the disease is stroke disorder.