Oral administration of some whey proteins products (specially WPH and WPI) improved the fatty liver state in a rat model of NAFLD, which is in correlation with the results of histological examination of rats' liver and a reduction in hepatic triglycerides, liver enzymes levels (ALT and AST), serum glucose and lipid peroxidation (MDA). This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.