In order to explore the potential mechanisms underlying the dysregulation of the Nrf2/Keap1 system in the pancreatic cancer cell line panel, we sequenced the protein-coding exons 2-6 of the KEAP1 gene and exon 2 of NRF2, which have been shown to contain functionally relevant SNPs in other cancer types [24]. This evidence concerns the gene NFE2L2 and pancreatic neoplasm.