In order to analyze the relationship between gelatinolytic pattern in biopsy prints and the grading of prostate tumours we categorized the results obtained by zymogram analysis according to the following relative score (gelatinolytic score, GS): 0 for no gelatinolytic activity; 1 for diffuse gelatinolytic activity; 2 for discrete gelatinolytic activity (MMP-2 or MMP-9). This evidence concerns the gene MMP2 and prostate neoplasm.