MKI67 and cancer: Fig. 9 (a) presents two histopathological images (H&E) of representative tumor sections of the synovial sarcoma cell line SW982. In the control xenografts, the tumor contains large numbers of dense, highly proliferative cancer cells. The decrease in tumor staining, a poor nuclear-to-cytoplasmic ratio, and the loose structure in the [D]-K3H3L9 treated mice indicates a massive tumor cell death. This was further verified with Ki67 immunohistochemistry stainings. Fig. 9 (b) shows the results of the HPF-counting of both cell lines.