Whole-genome microarray analysis was used to identify transcripts altered in human psoriasis and each of five mouse psoriasiform phenotypes (back skin of K5-Tie2 transgenic mice, back skin of IMQ-treated mice, both ear and tail skin of K14-AREG transgenic mice, back skin of K5-Stat3C mice, and back skin of K5-TGFβ1 mice; see representative images of each phenotype in Figure 1). The gene discussed is TEK; the disease is psoriasis.