In human psoriasis, expression of CLEC7A was elevated 8.7-fold (FDR-adjusted P<1.59×10−58), but expression of the mouse ortholog Clec7a was not altered in the K5-Tie2 phenotype (P = 0.843) and was decreased by 43% in the IMQ phenotype (P = 0.046) (Figure 5A). Here, TEK is linked to psoriasis.