Mitosis-associated transcripts were most strongly elevated in K5-TGFβ1 lesions, and a comparable trend was evident for K5-Tie2 lesions, and in this regard, the K5-TGFβ1 and K5-Tie2 models were generally most similar to the mitotic gene expression signature of clinical psoriasis (see Figure S12). The gene discussed is TEK; the disease is psoriasis.