Nevertheless, data on patients with overt and/or latent viral infections are lacking and in our opinion, more studies are needed to explore the potential effect of R on latent viral infections (for example, herpesvirus and HBV infections) and on selected groups of patients (for example, patients with advanced HIV infection, anti-HBc positive and/or HBsAg positive patients). The gene discussed is KRT88P; the disease is HIV infectious disease.