Some examples of deletion/enhancer effect involve the regulation of pleckstrin homology domain containing, family F (with FYVE domain) member 1(PLEKHF1), and Parkinson disease (autosomal recessive, early onset) 7 (PARK7), and of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) as deletion/repressor effect. The gene discussed is FDFT1; the disease is Parkinson disease.