IL1B and chorioamnionitis: Moreover, loss of the ileal barrier in utero such asseen in our translational model following IL-1 driven intestinal inflammation mightexplain the association between chorioamnionitis and the increased risk for adverseoutcomes of the gut, since gut barrier loss is not only associated with poornutrition and subsequent postnatal growth restriction, but also contributes tointestinal pathologies after preterm birth including necrotizing enterocolitis [24].