Conversely, LCA inhibitedEphA2 phosphorylation induced by ephrinA1-Fc in PC3 and HT29 human prostate andcolon adenocarcinoma cell lines (IC50 = 48 and66 μM, respectively) without affecting cell viability or other receptortyrosine-kinase (EGFR, VEGFR, IGFR1β, IRKβ) activity. Here, KDR is linked to adenocarcinoma.