The cytokine IL1β, identified by the IPA analysis as linkedto the activation of the pro-metastatic chemokines CX3CL1 andCCL20 (Figure 4A), was up-regulated in the tumour cellpopulations PIN and H-PCA (Figure 5A, and 5C), whereas the expression ofIL1R1, which mediated the activity ofIL1β, follows an opposite trend (Figure 5A, B and C). This evidence concerns the gene CX3CL1 and neoplasm.