CTNNB1 and neoplasm: In the present study, expression of CD44 extracellular domain, Zo-1, occludin, MMP-7, and laminin-5γ2 in association with beta-catenin nuclear localization, and levels of sialyl LeX were immunohistochemically investigated along with tumor budding in UC-associated and sporadic colon carcinomas, with the aim of elucidating differences in mechanisms of invasion and biological behavior between the two types of colon carcinomas in relation to prognoses.