INS and Hypoglycemia: In the present study, the overall hypoglycemia rates observed with blood glucose concentrations < 40 mg/dl in 0.9% and < 80 mg/dl in 10.9% (Table 1) were low, furthermore the administration of insulin was associated with an increased risk of blood glucose concentrations < 80 mg/dl (OR 2.1; 95% CI 1.7 - 2.6) (Table 3).