Androgens are known to have a role in the progression of prostate cancer (Gelmann, 2002; Verras and Sun, 2006), in which a crosstalk between the androgen receptor and canonical Wnt pathways has been identified at several levels in these signalling pathways (Truica et al, 2000; Feldman and Feldman, 2001; Balk, 2002; Mulholland et al, 2002; Chesire and Isaacs, 2003). This evidence concerns the gene AR and Familial prostate cancer.