Failed interactions between RB1 and NCAP-D3 in primary and tumor cells therefore result in loss of chromosome segregation fidelity, aneuploidy, micronuclei and anaphase bridges, all of which were observed in LmnaDhe/+ cells as well [7], [13]–[15], [19]–[22], [24]. This evidence concerns the gene NCAPD3 and neoplasm.