The CC chemokine subfamily themselves (for example, chemokine (C-C motif) ligand 5 (CCL5; also known as 'regulated upon activation, normal t cell expressed, and secreted' (RANTES)), CCL3 (macrophage inflammatory protein (MIP)-1α), CCL4 (MIP-1β), CCL2 (monocyte chemotactic protein-1 (MCP-1))) have been shown to straddle the continuum from type 1 to type 2 immune responses making these chemokines likely candidates to be involved in the overall pathogeneses of pulmonary sarcoidosis [13]. This evidence concerns the gene CCL3 and pulmonary sarcoidosis.