Cyclin D1 islikely to be related to both tumor initiation and progression and may play a keyrole in promoting growth of glial cells and their transformation to malignant cells.A characteristic feature of cancer is uncontrolled cell division and disruption of asteady stage between apoptosis and cell division by loss of cell cycle control,which deregulates G1-S phase progression. Here, CCND1 is linked to cancer.