hUCBSC when co-cultured with glioma cellsdepicts both fascaplysin and thymidine activity in part, by showing reducedG0-G1 phase, reduced cyclin D1 and Cdk 4 expressionlevels, and increased G0-G1 phases with decrease in thecyclin D1 and Cdk 4 expression levels. The gene discussed is CCND1; the disease is central nervous system cancer.