Several studies have demonstrated that a level of serum ferritin <1000 μg/L is an accurate predictor for the absence of cirrhosis, independent of the duration of the disease.47–49 A serum ferritin level >1000 μg/L with an elevated aminotransferase level (alanine aminotransferase [ALT] or aspartate aminotransferase [AST]) and a platelet count <200 × 109/L predicted the presence of cirrhosis in 80% of C282Y homozygotes.50 The gene discussed is GPT; the disease is Cirrhosis.