CD4+ T-cell subsets have been implicated in tumor rejection induced by vaccination of mice with CCL19-transduced tumor cells [26], and CD8+ CTL were instrumental in tumor growth rejection in mice following intratumoral delivery of CCL20 or CXCL12 via adenovirus vectors [27] or injection of CCL16-expressing tumor cells. The gene discussed is CD8A; the disease is neoplasm.