CCR5 and neoplasm: In these studies, favorable prognosis was correlated with the presence of tumor cells secreting chemokines such as CCL5, CXCL10 and CXCL1 that played a role in recruitment of CCR5+/CXCR3+ T-helper (Th)1 cells or CX3CR1+, perforin+/granzyme B+ T cells [17], [18].