Reduced HIV infection was associated with siRNA mediated reduced expression of the oxidative glycosylases OGG1, MYH, NTH1, NEIL2, NEIL3, the endonuclease APE1, the polymerases POLB, POLI, POLL and the ligase proteins LIG3 and XRCC1 in human cells [6]. This evidence concerns the gene MUTYH and HIV infectious disease.