Studies of peripheral blood mononuclear cells as well as of human breast, colon and prostate cancer cell lines suggest a cell-type-specific role for vimentin in cell adhesion, motility and invasiveness (Nieminen et al, 2006; Ivaska et al, 2007; McInroy and Määttä, 2007; Zhao et al, 2008). This evidence concerns the gene VIM and Familial prostate cancer.